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How many subtypes of H1 receptors have been identified?


A) Two
B) Three
C) Four
D) Five

E) C) and D)
F) None of the above

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Antihistamines are used for the treatment of:


A) allergies.
B) anaphylactic reactions.
C) depression.
D) both A and B.

E) All of the above
F) B) and D)

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D

Blocking which histamine receptor would help in the management of excessive gastric acid secretion?


A) H1
B) H2
C) H3
D) H4

E) B) and C)
F) All of the above

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Which secondary messenger is associated with H1 receptor activation?


A) IP3
B) Cyclic AMP
C) DAG
D) Both A and D

E) C) and D)
F) B) and C)

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Where are H1 receptors found?


A) Stomach
B) Smooth muscles
C) Immune cells
D) All of the above

E) B) and C)
F) C) and D)

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First-generation antihistamines have a longer duration of action.

A) True
B) False

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False

Which route of administration is preferred is hypovolaemic shock occurs?


A) Intravenous
B) Oral
C) Rectal
D) Transdermal

E) A) and B)
F) A) and C)

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Which of the following mediators plays a role in modulating allergic reactions?


A) Serotonin
B) Histamine
C) Pepsin
D) None of the above

E) A) and B)
F) A) and C)

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B

In comparison to second-generation antihistamines,first-generation antihistamines cause more:


A) orthostasis.
B) nausea.
C) sedation.
D) vomiting.

E) C) and D)
F) A) and B)

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